The Journal of Cultural Mediation of the SSML Fondazione Villaggio dei Ragazzi “don Salvatore d'Angelo” focuses on the role of culture in perceiving and translating reality. The interplay between language and culture in communication is a fundamental issue and, now more than ever, needs to be investigated. The greatest challenge of today’s society is managing diversity. In fact, more and more people are becoming involved in communicative interactions with “others” from different linguistic and cultural backgrounds. This continuous exchange happens in many different fields, as business, education, media, tourism and also through immigration and politics. Therefore, the aim of this Journal is to promote research in communication, especially by investigating language, languages, cultural models, mediation and interculturality. Each issue contains a selected number of interdisciplinary articles, themed around a central topic in intercultural communication.